CAPS2 and major depressive disorder: In addition, CAPS2 mRNA levels in postmortem habenula samples of depressive patients tended to decrease, being 73% of non-depressed controls (CON, n = 11; MDD, n = 12; Student’s t-test; fold change for CON vs. MDD suicides: for CAPS2, 1.00 ± 0.73 vs. 0.73 ± 0.42, T(21) = 1.111, P = 0.279; for CAMK2B, 1.00 ± 0.38 vs. 1.11 ± 0.38, T(21) = -0.714, P = 0.483; Fig. 1c and d).