Therefore, LIMD1, DAB2IP, SASH1, MCC, RASSF2, RECK, CBFA2T3, GPC3, KLK10, STARD13, CDKN1C, LATS2, RAP1A, FOXP1 and DCC can be used for diagnosis of early NSCLC patients. The gene discussed is RASSF2; the disease is non-small cell lung carcinoma.