PIK3CA and cancer: PIK3CA, LIMD1, KCNRG, DDX5, DAB2IP, APC, TRIM13, KLK10, NBL, EXT1, and TBRG1 had \documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$${S}^{+}$$\end{document}S+ < 0.1, so they had weak network effects on gene expression in stage-2 cancer (Fig. 4).