CAV1 and cancer: Loss of Cav-1 has previously been shown to correlate with poor survival in other cancers, for example prostate83 and breast84, in agreement with the Onion study but given the discrepancies identified in this analysis, further studies assessing the prognostic role of Cav-1 in CAFs in NSCLC would be warranted to clarify its prognostic role in lung cancer.