Our samples #3, #5 and #6 – all examined as adenocarcinoma, all got treated with radiochemotherapy protocol according to CROSS trial, CXCR4 expression was determined in the surgical specimen – ranged from none to intermediate expression, as well as the squamous cell cancer (SCC), which ranged up to strong expression (#4, #7) fixed in OGD sampling [40]. Here, CXCR4 is linked to squamous cell carcinoma.