PTEN and non-small cell lung carcinoma: For example, myeloid phosphate and tension homology deleted on chromosome ten (PTEN) promoted chemotherapy-induced NLRP3 mediated cell pyroptosis to inhibit cancer development [29], and activation of NLRP3-mediated pyroptotic cell death enhanced the cytotoxic effects of cisplatin in non-small cell lung cancer (NSCLC) [30].