We have looked at the glycosyltransferases which were previously found altered and responsible for changes on secreted N-glycans in ovarian cancer [7] and found that MGAT5 and ST3GAL4 correlated with increases in highly branched and sialylated structures on secreted glycans in the chemo-sensitive ovarian cancer cell lines. The gene discussed is ST3GAL4; the disease is ovarian carcinoma.