The results showed that 12 DEGs (C1S, CFI, DCBLD2, FAM20C, FNDC3B, IFI30, KDELR2, RCAN2, PLP2, SERPINH1, STEAP3, and TNFRSF1A) were significantly correlated with the OS rate of patients with GBM (p < 0.05) (Fig. 5). The gene discussed is PLP2; the disease is glioblastoma.