Quantitative RealTime PCR analyses demonstrated strong significant overexpression of CFL1 mRNA in pancreatic tissue (n = 12) both in comparison to healthy pancreas tissue (n = 8) from organ donors (p = 0.0005) as well as to chronic pancreatitis (C.P., n = 9) cases (p = 0.00008), while expression in chronic pancreatitis and healthy pancreas were not significantly different (p = 0.54) (Figure 1a). This evidence concerns the gene CFL1 and chronic pancreatitis.