In general, sepsis still has a high morbidity and mortality rate in the rescue and treatment of critically ill patients.[15] Although there has been some progress in the understanding and treatment of sepsis with the development of medical treatment, the prognosis of sepsis is still not optimistic.[16] Some clinical trials have found that serum H-FABP in patients with sepsis is on the rise, but the value of H-FABP in the prognosis of patients with sepsis is currently not systematically reviewed or meta-analyzed. Here, FABP3 is linked to Sepsis.