Abbreviations: ADP = adenosine diphosphate, APD = antiplatelet drug, APDs = oral antiplatelet drugs, APTT = activated partial thromboplastin time, CFRT = conventional fractionated radiotherapy, EC = esophageal cancer, PSM = propensity-score matched, PT = prothrombin time, rhlL-11 = recombinant human interleukin-11, TPIAO = recombinant human thrombopoietin injection, TPO = thrombopoietin, VMAT = volumetric modulated arc therapy. The gene discussed is THPO; the disease is esophageal cancer.