Anti-VEGF or laser photocoagulation for diabetic retinopathy (1); anti-VEGF vs sham for macular edema secondary to central retinal vein occlusion (3); anti-VEGF vs sham for macular edema secondary to branch retinal vein occlusion (1); anti-VEGF vs sham for choroidal neovascularization secondary to pathological myopia (1); ocriplasmin injection vs sham for symptomatic vitreomacular traction (1); ocriplasmin injection vs sham for symptomatic vitreomacular adhesion (1). The gene discussed is VEGFA; the disease is myopia.