By immunohistochemistry, although L1CAM was reported to be typically expressed in a diffuse and strong manner in ST ependymomas with C11orf95‐RELA (10, 11, 36, 37, 38), L1CAM expression was almost exclusively found in the embryonal‐appearing components in all cases of primary ELTMD and the recurrent tumor in case 2 regardless of the fusion partners of C11orf95 (Figure 3I). This evidence concerns the gene RELA and neoplasm.