In contrast, both LR and MLP classifiers resulted in large significant differences between control and ALS mutant groups irrespective of their genetic backgrounds (PLR|VCP = 1.4e‐04, PML|VCP = 1.2e‐04, PLR|SOD1 = 2.4e‐03 and PMLP|SOD1 = 3.3e‐03). This evidence concerns the gene SOD1 and amyotrophic lateral sclerosis.