fermentum MCC2759 and MCC2760 exhibited beneficial effects in HFD and type 2 diabetic models by improving glucose and lipid profile, reduction of pro-inflammatory cytokines in liver, intestine, MAT, and muscle tissue, and improving the intestinal barrier function and expression of GLUT4, GLP1, and adiponectin. Lact. Here, ADIPOQ is linked to type 2 diabetes mellitus.