NRs involved in the progression of steatosis are the aryl hydrocarbon receptor (AHR), constitutive androstane receptor (CAR), estrogen receptor (ER), farnesoid-X-recptor (FXR), glucocorticoid receptor (GR), liver-X-receptor (LXR), peroxisome proliferator-activated receptor (PPAR) alpha, pregnane-X-receptor (PXR), retinoic acid receptor (RAR) and retinoid-X-receptor (RXR) (Mellor et al. 2016; Vinken 2015). The gene discussed is NR1I2; the disease is steatosis.