Previously, we showed that full ablation of Crb2 specifically in MGCs (Crb2ΔMGC) causes a slow progressing RP-like phenotype with sporadic disruptions at the OLM with protrusion of photoreceptor nuclei into the photoreceptor segment layer, similar to previous observations in retinas lacking CRB1, without effects on the ERG response.5 The gene discussed is CRB2; the disease is retinitis pigmentosa 1.