Collection: Convalescent plasma is generally collected by apheresis technology from patients who have had RT-PCR proven infection of COVID-19 and recovered symptomatically for at least 14 days and tested negative with fair certainty (demonstration of two non-reactive NAT for SARS-CoV-2 performed at an interval of 24 hours apart on nasopharyngeal swabs). The gene discussed is BRD2; the disease is infection.