PRKN and tuberculosis: In addition to the 4833415N18Rik and H2-Oa genes, several other DE genes that have been up- or downregulated in this study have also been reported to be associated with tuberculosis, including Park2, Sp110, Dusp4, and Klrk1. The Park2 gene encodes the protein parkin RBR E3 ubiquitin protein ligase, which is a ubiquitin ligase that plays an essential role in mitochondrial phagocytosis.