Nevertheless, in the regression phase, the mTOR expression was reduced due to the effect of some mechanism, which inhibited the phosphorylation of p70S6K-α, blocked the cell cycle in the G0/G1 phase, and then accelerated the apoptosis of vascular endothelial cells of hemangioma, with a tendency of spontaneous regression for hemangioma [21]. Here, RPS6KB1 is linked to hemangioma.