The univariate analysis showed that T stage (HR = 1.668 [1.184–2.349], P = 0.003), N stage (HR = 2.606 [1.939–3.503], P<0.001), M stage (HR = 2.111 [1.232–3.616], P = 0.007), pathologic stage (HR = 2.975 [2.188–4.045], P<0.001), primary therapy outcome (HR = 2.818 [2.004–3.963], P<0.001), residual tumor (HR = 3.973 [2.217–7.120], P<0.001), tumor status (HR = 6.211 [4.258–9.059], P<0.001), and GCC2-AS1 expression (HR = 1.560 [1.164–2.092], P = 0.003) were significantly correlated with the OS time of LUAD patients (Table 2). Here, GCC2 is linked to neoplasm.