The gene network analysis showed HDAC1 (Histone Deacetylase 1), RASA1 (RAS P21 Protein Activator 1), and Prostatitis and urethral stricture associated and coregulator of androgen receptor activity KLK3/(PSA) (Kallikrein Related Peptidase 3) gene tightly associated with MYC transcription factor in young-rPSA group. The gene discussed is KLK3; the disease is urinary system disorder.