CD79A and infection: Saliva consists of locally produced substances plus serum components that can be useful in the diagnosis of various systemic diseases and oral manifestations.6 The most crucial specific defense factors of saliva are immunoglobulins (Ig), in which the secretory IgA (sIgA) is predominant, produced by the plasma cells in the salivary glands, which is essential in local (mucosal) immunity.7 A fully responsive immunologic system is essential to encounter various infections and toxic agents.