SLC7A11 is upregulated in oral squamous cell carcinoma (OTSCC), excessive intracellular ROS accumulation, increased O2 concentration, and inhibition of SLC7A11 expression, leading to postirradiation induced ferroptosis, a nanomedicine formed by the combination of the photosensitive agent Ce6 and thickening inducer erastin, and produces good antitumor effects in transplanted tumor mouse models with low other tissue cytotoxicity [105]. The gene discussed is SLC7A11; the disease is neoplasm.