In this study, melanoma patients showed higher levels of VEGF-A, PDGF-BB, IL-1RA, PIGF-1, IFN-γ, TNF-α, MIP-1α, and SCF, but decreased levels of BDNF, SDF-1α, MCP-1, Eotaxin, EGF, and IL-7 than those in healthy patients. This evidence concerns the gene CCL3 and melanoma.