PDC and primary biliary cholangitis: Similar observations were made in NSG hosts reconstituted with PBMCs from DRB4*0101+ or DRB1*0801+ PBC patients in response to treatment with PDC-E2122-135/DRB4*0101-, PDC-E2249-262/DRB4*0101-, and PDC-E2629–643/DRB1*0801-NPs (Table 1).