In NAFLD, the results showed that the immune infiltration of the following cells increased (CD4_naïve cells, Tr1 cells, Th1 cells, Central memory cells, Dendritic Cells (DCs), B cells, NK cells, CD4 T cells, and CD8 T cells), while the immune infiltration of Tfh cells and Neutrophil decreased (Figure 8F). Here, CD4 is linked to metabolic dysfunction-associated steatotic liver disease.