The results showed that classifiers have better accuracy and reliability (AUC=0.953, 0.730, 0.910) than PNPLA3 (AUC=0.579, 0.639, 0.565) to distinguish NAFLD states (Normal/NAFL/NASH) (Figures 5O–Q). This evidence concerns the gene PNPLA3 and metabolic dysfunction-associated steatohepatitis.