Besides, consuming CD11c + DCs or CD103 + DCs reduced proinflammatory cytokine and liver fibrosis in MCD-induced NASH or thioacetamide-diet–induced liver fibrosis models proved DCs also played a pro-inflammatory role in the NAFLD process (28, 64, 65). The gene discussed is ITGAX; the disease is metabolic dysfunction-associated steatotic liver disease.