The Kir2.1 channel and the Kir3.1 channel were highly expressed both in the OSA group and the OSA+LLVS group compared with those in the control group (p<0.01), and no significant difference was observed between the OSA group and the OSA+LLVS group (p>0.05). The gene discussed is KCNJ3; the disease is obstructive sleep apnea syndrome.