SCN5A and obstructive sleep apnea syndrome: In our present study, we evaluated the level of ion channels through detecting the gene expression with qRT-PCR, and found that a higher expression of Nav1.5 was manifested in the OSA group, followed by a decreased level in the OSA+LLVS group, which was in line with previous studies (Chatelier et al., 2012; Makara et al., 2014).