In terms of genetic etiologies, several genes, including UMOD (OMIM 16p12.3 and 191845)2, REN (OMIM 1q32.1 and 179820)5, HNF1B (OMIM 17q12 and 189907)4 and MUC1 (OMIM 1q22 and 158340)3 have been confirmed to be responsible for some forms of ADTKD. This evidence concerns the gene MUC1 and autosomal dominant medullary cystic kidney disease with or without hyperuricemia.