Interestingly, all FL patients were grouped in the low-risk group of all-cause mortality based on the 5hmC levels of CNN2 and HMG20B. For CNN2, of the 10 DLBCL patients in the low-risk group of death, 4 of the 5 patients with known cell-of-origin data were the GCB-type, which typically has better prognosis than the ABC-type of DLBCL. Here, CNN2 is linked to diffuse large B-cell lymphoma.