These included genes related to cancer (cell immortalization and transformation) and genes previously reported to be methylated in ALL (CDH1, p73, p16, p15, p57, NES-1, DKK-3, CDH13, p14, TMS1, APAF-1, DAPK, PARKIN, LATS-1 and PTEN). This evidence concerns the gene CDKN2A and cancer.