These included genes related to cancer (cell immortalization and transformation) and genes previously reported to be methylated in ALL (CDH1, p73, p16, p15, p57, NES-1, DKK-3, CDH13, p14, TMS1, APAF-1, DAPK, PARKIN, LATS-1 and PTEN). The gene discussed is CDKN2A; the disease is acute lymphoblastic leukemia.