CXCL8 and neuroblastoma: In the case of IL-8 +781 C > T rs2227306, we found a higher frequency (88.9% vs. 57.9%) of CC + CT genotypes in patients with NB compared to the control group (p = 0.011) and a significant difference (p = 0.027) in the distribution of the homozygous TT genotype, which had a higher frequency (42.1% vs. 11.1%) in healthy children compared to patients with NB.