CD4 and Huntington disease: Our present results show that HD/ASCs and AS/ASCs, co-cultured with activated CD4+ T cells (Figure 1) or PBMCs (Figure 2), have little effect on the expression of T-bet, but up-regulate the levels of GATA3, RORc, and FoxP3 mRNAs, causing significant decrease in T-bet/GATA3 and RORc/FoxP3 ratios in CD4+ T cells.