Tauvid is reported to have high affinity to immunopurified PHF-tau from postmortem human AD brain tissue with a KD value of 0.68 nM by homologous competition [33], and a KD value 0.57 nM with a Bmax of 309 pmol/mg protein as determined by a saturation binding experiment [32,33]. This evidence concerns the gene MAPT and Alzheimer disease.