In TGCT tumors, miR-223-3p upregulation provokes the inhibition of apoptosis mediated by the F-box/WD repeat-containing protein 7 (FBXW7), which belongs to a protein complex acting as a tumor suppressor that sustains the degradation of oncoproteins, including c-Myc, cyclin E, MCL-1, c-JUN, NFκB2 and Notch1 [84]. Here, FBXW7 is linked to neoplasm.