There was no clinical manifestation of GI abnormality as evidenced by similar bodyweight of FcgRIIb-/- vs. WT mice at baseline (0 h time-point) (Figure 1B), despite a mild immune deposition in the gut of lupus mice with PBS control (Figure 3E–H and 5). The gene discussed is FCGR2B; the disease is systemic lupus erythematosus.