Interestingly, the common findings in lupus nephritis [36] including proteinaceous casts, red blood cell casts (Figure 1J; arrow heads and dotted line arrow) and glomerular IC deposition (Figure 2) at 7 days of the experiments were prominently presented in FcgRIIb-/- mice, but neither WT mice nor PBS-control FcgRIIb-/- mice, suggesting an exacerbation of lupus activity by NSAIDs. Here, FCGR2B is linked to lupus nephritis.