To do this, we used leukemia K562 cells with high and moderate expressions of ABCB1, K562/DoxDR3 and K562/DoxDR2, and ABCG2, K562/ABCG2CL10 and K562/ABCG2CL4, respectively (Figure 3). The gene discussed is ABCB1; the disease is leukemia.