Fibroblast cell-lines obtained from one BBS patient with pathogenic variants in BBS1 (named BBS1−/−), two patients (siblings) with pathogenic variants in BBS5 (named BBS5−/−(A) and BBS5−/−(B), respectively) and two BBS patients with pathogenic variants in BBS10 (named BBS10−/−(A) and BBS10−/−(B), respectively) (Table 1), and three anonymous control samples named Ctrl.A, Ctrl.D and Ctrl.E, were investigated. The gene discussed is BBS5; the disease is Bardet-Biedl syndrome.