Interestingly, in one series only 77/1385 (6%) NSCLC patients harbored an STK11 mutation according to next generation sequencing (NGS) analysis while the AACR genie database (v8.1 public) reported STK11 mutations in 1495/14,303 (10.5%) of samples [92]. The gene discussed is STK11; the disease is non-small cell lung carcinoma.