Selective loss of GSK-3β in the forebrain pyramidal neurons produced anxiolytic (reduced anxiety) and pro-social effects [31], and loss of GSK-3β but not GSK-3α in GABAergic neurons, reversed gamma oscillation deficits and cognitive dysfunction in an NMDA hypofunction model related to schizophrenia [32]. Here, GSK3B is linked to schizophrenia.