In patients without lymph node metastases, high PARP1 expression was significantly associated with thick (according to the Breslow scale), ulcerated, and highly mitogenic primary tumors (p = 0.0016, p = 0.023, and p < 0.001) (Table 3), whereas in patients with nodal metastases, upregulation of PARP1 correlated with the presence of microsatellitosis (p = 0.034) (Supplemental Table S1). The gene discussed is PARP1; the disease is metastatic malignant neoplasm in the lymph nodes.