The main molecular subtypes are: (a) luminal (ER and PR positive); (b) HER-2 enriched (ER, PR negative, and HER-2 overexpression), and (c) triple-negative breast cancer (TNBC) (ER, PR, and HER-2 negative) [4,5,6]. Here, ERBB2 is linked to triple-negative breast carcinoma.