To verify this hypothesis, we performed genome wide transcriptional comparison of CD34+ HSPCs isolated from the sternal BM biopsies of both normoglycemic and T2DM coronary artery disease patients (CAD and CAD-DM, respectively) undergoing coronary artery bypass graft (CABG) A total of 23 patients, 11 CAD (controls) and 12 CAD-DM (cases) matched for gender and with similar age, were enrolled (Table 1). This evidence concerns the gene CD34 and type 2 diabetes mellitus.