PPBP and myocardial infarction: In addition to non-coding RNAs, several bioactive proteins such as Apolipoprotein D (APOD) and Apolipoprotein C3 (APOC3) (lipid metabolism), C1Q1A and C5 (complement activation), Glycoprotein Ib Platelet Subunit Alpha (GP1BA), and Pro-Platelet Basic Protein (PPBP) (platelet activation pathways) have been identified in exosomes from patients suffering from MI, and thus may be used as biomarkers for myocardial injury [120].