A predominant involvement of cancer related molecular alterations was observed, for instance, (i) overrepresentation of AR transcriptional activity reported by the upregulation of AR targets: KLK3 and heat shock protein (HSPs): HSP90AB1 (Figure S6J) and (ii) enrichment of cancer associated proteoglycans, such as Cortactin (CTTN) (Figure S6K). The gene discussed is AR; the disease is cancer.