In this study, higher frequency of NKp30+ NK cells 1 day after RFA correlated to lower tumor recurrence, whereas a delayed increase of total NK cells and higher percentages of CD56bright NK cells at 1 month after RFA were associated with more tumor recurrence in patients with HCC [56], suggesting that NK cell dynamics play an important role in response to this therapy. The gene discussed is NCR3; the disease is neoplasm.