Several urinary proteins have been reported as potential predictors of LN activity, in particular NGAL (neutrophil gelatinase-associated lipocalin), MCP-1 (monocyte chemoattractant protein-1), TWEAK (tumor necrosis factor-like weak inducer of apoptosis), and PTGDS (prostaglandin D synthase) [40,41,42,43,44,45,46]. This evidence concerns the gene PTGDS and lobular neoplasia.