Significant risk factors for relapse in univariate analysis were tumor size (HR = 1.21, 95% CI: (1.04–1.40), p = 0.01), Hb level (HR = 0.84, 95% CI: (0.72–0.97), p = 0.02), RDW (HR = 1.16, 95% CI: (1.05–1.28), p = 0.003), and HRR as both a continuous variable (HR = 0.15, 95% CI: (0.05–0.50), p = 0.002) and categorized according to its median cut-off (HR = 0.41, 95% CI: (0.25–0.68), p < 0.001); pT2 and pT3 stages but not pT4 also showed an increased hazard for relapse compared to pT1, as well as Stages 2A, 2B and 3A, 3B vs. Stage 1A,1B (Table 2). This evidence concerns the gene GSTM1 and neoplasm.