For this reason, Sun et coll.—considering that Hb is a well-established marker of nutritional status—combined RDW and Hb values to build a new prognostic index for esophageal squamous cell carcinoma, disclosing a significant association between the HB/RDW ratio and clinical characteristics and survival outcomes in this cohort of patients [4]. The gene discussed is GSTM1; the disease is esophageal squamous cell carcinoma.