MIR205HG and neoplasm: This may implicate that CAFs that have been activated by tumor cells in a given area of the prostate gland may induce, in a sort of ‘field effect’, pathogenic effects on surrounding normal cells, such as the impairment of basement membrane deposition (regulated by miR-205) or an uncontrolled basal-luminal differentiation (regulated by MIR205HG/LEADR).