TET2 and lung cancer: Lung cancer-derived exosomal miR-210 was indeed reported to elevate the expression of proangiogenic factors, such as MMP9, FGF2 and vascular endothelial growth factor (VEGF), in recipient fibroblasts by modulating JAK2/STAT3 signaling pathway and ten-eleven translocation 2 (TET2) [86].