Notably, the median PFS was 2.8 months (95% confidence interval (CI), 2.6–3.2) for D842V-mutant GIST patients compared to 28.5 months (95% CI, 5.4–51.6) for that of subjects with other PDGFRA mutations (p = 0.0001) [10]. The gene discussed is PDGFRA; the disease is gastrointestinal stromal tumor.