In a study conducted by Agaimy and colleagues where the authors evaluated a combined histomorphological–immunohistochemical pattern analysis of GIST with PDGFRA mutations, PDGFRA-mutant GIST were more frequently epithelioid compared to KIT-mutant GIST (p < 0.001) [24]. This evidence concerns the gene PDGFRA and gastrointestinal stromal tumor.