PIK3CA and neoplasm: Missense mutations in DDR2 (L610F), BRAF (G15V), FGFR2 (F645L), MET (T992I), NRAS (A155T) and PIK3CA (G106V) could each be outlined in one (3.7%) of the tumor specimens, respectively, but none of these were co-occurring in one and the same biopsy sample.